To disable startup apps with the Task Manager, press Ctrl+Shift+Esc to open Task Manager, then switch to the Startup tab. Select the program you want to disable from the list, then click "Disable" in the bottom right corner. You can also right-click a program on the list to remove it.
You can disable Startup Apps & Programs on a Windows computer by using Settings, Task Manager and also by removing them from the Startup Folder.